A team of researchers, including four from UC Berkeley, developed a new painkiller compound that is less addictive and less likely to cause fatal overdoses from respiratory depression than morphine.

(A) Binding energies of (-)-morphine and (+)-morphine interacting with MOR. (B) Binding pocket residues of (-)-morphine and (+)-morphine in MOR, visualized from the extracellular side. (C) W293 ...

A novel compound strongly improves the efficacy of naloxone, the substance used to reverse overdoses of morphine, fentanyl and other opioid drugs. When administered to mice along with naloxone, it is ...

A paper published by the Journal of Neuroinflammation reported a key immune system component could be blocked to make morphine treatment more effective by blocking its frequent painful side effects, ...

Opioids are some of the oldest known treatments for pain relief, but they can cause serious side effects. A team of researchers including Susruta Majumdar, a medicinal chemist and pharmacologist at ...