We describe the dynamics of kinetochore dynein–dynactin in living Drosophila embryos and examine the effect of mutant dynein on the metaphase checkpoint. A functional conjugate of dynamitin with green ...

Researchers have proposed a novel molecular mechanism for the living cell's remarkable ability to detect the alignment of replicated chromosomes on the mitotic spindle in the final phase of the cell ...

Researchers from Virginia Tech and Oxford University have proposed a novel molecular mechanism for the living cell's remarkable ability to detect the alignment of replicated chromosomes on the mitotic ...

Cell cycle checkpoints prevent transition from one phase of the cell cycle to the next until all processes of the present phase are completed. Defects in the checkpoint functions result in gene ...