Chatting to me ahead of the Marvel series' two-episode premiere, Jeff Trammell was reluctant to go into detail on where the story will go next. However, Trammell, who's also the animated project's head writer and one of its executive producers,

Man’s placement in the endless web known as the Marvel Cinematic Universe, executive producer Dana Vasquez-Eberhardt said something happens in the new Disney+ show that branches it off from the traditional timeline Tom Holland’s Spider-Man occupies.