A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...

Proteins are the 'workhorses' in every living cell and constitute the chemical basis of life. These little machines are required to turn food into energy, to manage motion and brain activities and to ...

Osaka, Japan – Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a microscopic scale. However, the precise mechanisms that ...

AI protein function prediction uses machine learning models trained on sequence and structural data to infer protein roles at scale. Techniques such as transformer-based models enable automated ...

Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this capability is a novel modular design strategy developed by researchers at ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...