Linear mixed models are increasingly used for the analysis of genome-wide association studies (GWAS) of binary phenotypes because they can efficiently and robustly account for population ...

We investigate in this paper the Lagrangian duality properties of linear equality constrained binary quadratic programming. We derive an underestimation of the duality gap between the primal problem ...

This is a preview. Log in through your library . Abstract Longitudinal studies of a binary outcome are common in the health, social, and behavioral sciences. In general, a feature of random effects ...