Maryland State Police troopers responded to southbound Interstate 81, north of Halfway Boulevard for a report of a seven-vehicle crash.

One southbound lane is closed on Interstate 81 in Sullivan County on Friday following a multi-vehicle crash, according to the ...

A multi-vehicle crash has caused a fuel spill on Interstate 81 southbound, according to 511NY at the Exit 12 ramp to ...

The northbound side of I-81 was closed at Exit 52A. Units with the Pennsylvania State Police in Carlisle handled the response ...

A crash closed all lanes of Interstate 81 northbound in Schuylkill County early Wednesday morning, according to PennDOT.

One person is dead after a crash with a tractor trailer on Interstate 81 in Rockbridge County on Thursday afternoon. Domingo Sanchez-Lopez, 23, of Roanoke, was transported to Rockbridge Community ...

A deadly one-vehicle crash occurred on Interstate 81 at the Exit 5 ramp to Route 16 shortly after 7:30 p.m. Sept. 15.

A tractor-trailer crash has shut down the northbound lanes on Interstate 81 Monday evening, dispatch said. The ...

An 81-year-old man died following a two-vehicle crash on Interstate 81 in Butler Township, on Tuesday, according to Pennsylvania State Police Frackville.

DAUPHIN COUNTY, Pa. — A Schuylkill County woman has died following a fatal crash on Interstate 81 Northbound in Dauphin ...