Flow cytometry enables researchers to label proteins of interest using fluorophore-conjugated antibodies and other fluorochromes. Much like immunohistochemistry, which produces two- or ...

In the rapidly advancing field of immuno-oncology research, there has been increasing focus on the utility and optimization of cell humanized mice for translational research. Conventional murine ...

Humanized immune system (HIS) mice are invaluable for advancing preclinical research, with various models available to support lymphoid, myeloid and/or specific cell populations. T and NK cells are ...

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. According to their new study in ...

Since the development of the super immunodeficient CIEA NOG mouse® in the early 2000s enabled improved humanized immune system (HIS) mice, HIS models have been widely adopted in immuno-oncology ...

Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company utilizing its novel proprietary ARCUS® platform to develop in vivo gene editing therapies for high unmet need diseases ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

Trastuzumab is a common treatment for various HER2-positive cancers. It is an antibody that specifically binds to HER2, a problematic protein over-expressed on cancer cells that signals for nonstop ...

Scientists at Ghent University have created a mouse model that incorporates human versions of the receptors that recognize the fragment crystallizable (Fc) region of immunoglobulin G (IgG), one of the ...

Jackson Lab plans to renovate an existing 3,500-square-foot facility on the Bar Harbor campus, expand capacity and meet ...