NFL Week 16 picks against spread
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We’ve talked a lot about road favorites this season in the NFL, because they’ve done pretty well. According to TeamRankings.com, road favorites this seaosn were 52-29 against the spread going into Week 16.
Just four weeks are left in the 2025 NFL regular season, so let's be sure to take advantage of every opportunity we have remaining to bet. If you're looking to
The Philadelphia Eagles (9-5) are listed as touchdown favorites when they visit the Washington Commanders (4-10) in an NFC East matchup on Saturday, December 20, 2025 at Northwest Stadium. The over/under has been set at 44.5.