A study has traced thousands of conserved regulatory elements back 300 million years, revealing deep principles of plant ...

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only ...

While the large proportion of our genome that does not instruct our cells to form proteins has been harder to study than protein-coding genes, it has been shown to have vital physiological functions.

Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team identified promising sequence variants linked to various ...

The expression pattern of a single gene or multiple genes can be investigated using a technique RNA microarray. In this technique, RNA molecules are ‘spotted’ onto a solid surface. These act as probes ...

A novel bioinformatics approach for classifying proteins according to similarity of function, rather than of sequence, is described in the April 12 PNAS. Albert Y. Lau and Daniel I. Chasman of ...

Amgen manufactured and sold PCSK9 inhibitor Repatha whereas Sanofi manufactured and sold PCSK9 inhibitor Praluent, for the treatment of hyperlipidemia. In 2019, Repatha enjoyed a 70% share of the ...