Psoriasis is one of the most common chronic inflammatory skin diseases, affecting about 250,000 people in Austria. While previous treatment approaches have mainly focused on inhibiting ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as ...

Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

In a recent review published in the journal Cell Metabolism, a group of authors explored how Glucagon-Like Peptide-1 receptor (GLP-1R) agonism shapes the neurovascular unit (NVU), potentially linking ...