An extended follow-up to the ACCORD trial demonstrated no significant differences in CVD rate between statin-treated T2D patients randomized to concomitant fenofibrate and those randomized to masked ...

The drugs fenofibrate and gemfibrozil are considered fibric acid derivatives. They can reduce serum triglycerides by as much as 50% in some studies. The mechanism of action is complex. Fibrates ...

Presenting the results of the study at the American Diabetes Association 2007 Scientific Sessions, in Chicago, IL, lead investigator Dr Timothy Davis (University of Western Australia, Perth) said the ...

Both fish oil and fenofibrate safely reduce elevated triglyceride levels in HIV-infected patients receiving ART. High triglyceride levels are common among HIV-infected patients receiving potent ...

Q: My friends and I are all getting older, and I've noticed that some of them are on statins to lower their cholesterol. My doctor chose a fibrate for me, Lopid (gemfibrozil). What's the difference ...

Statins lower cardiovascular risk in patients with diabetes; however, as these patients are at higher risk than other cardiovascular patients, statins merely decrease coronary event rates to the level ...

A major meta-analysis of fibrate drugs has shown that they reduce the risk of major cardiovascular events, mainly through prevention of coronary artery disease and the need for revascularisation ...

Randomized controlled trials of fibrate therapy have yielded variable results. Although these agonists of peroxisome proliferator receptor alpha (PPAR-α) are known to reduce triglyceride levels and ...

Although recent evidence suggests that the clinical benefit may be uncertain for fibrates, a class of drugs used for the treatment of high lipid levels, use of these drugs is common in the US and ...

Certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas. These compounds were not previously ...

For many adults, eating a healthy diet filled with cholesterol-lowering foods doesn't budge their high cholesterol. That's when taking certain medications like statins can help. Statins are considered ...