The design of a two-color microarray experiment can be considered as having three layers. Figure 1 shows an example of an experiment that compares the effects of two treatments—A and B—on ...

Preclinical model systems are invaluable tools for drug discovery and development. But many complex diseases, such as nonalcoholic steatohepatitis (NASH), are difficult to recapitulate in the ...

Sound experimental design is of vital importance when conducting any scientific experiment. Choices made at the design stage have the potential to drastically impact the results of any study. A strong ...

The landscape of gene editing applications is expanding quickly. More and more, researchers are faced with choosing the right tools and protocols for genome engineering, including overexpressing ...

The application of experimental design methods to practical engineering problems is illustrated by an example involving road tests to measure how elevation affects octane requirements of automobiles.

Introductory quantitative skills required to conduct experimental research and analyze resulting data. Principles of measurement, modeling of experimental data, and statistical design of experiments.

One of the hottest debates in evolutionary biology concerns the origin of behavior: is it genetically encoded or do animals and birds copy their parents or other individuals? A classic experiment ...

Quantum designers: Florian Marquardt (left) and Leopoldo Sarra have shown how deep Bayesian experimental design can be applied to quantum many-body systems. (Courtesy: Leopoldo Sarra) As quantum ...

Dominguez-Rodrigo (2008) recently evaluated several studies of butchery experiments designed to interpret cut-mark patterns on fossil bones from FLK Zinj. He critiques my dissertation work, yet I ...