Neurofibrillary tangles mark Alzheimer’s disease and a plethora of primary tauopathies. How best to study them in the lab? Most mouse tauopathy models overexpress the human tau protein and are highly ...

Hidden inside every organ, microscopic fibers form a scaffolding that quietly shapes how we move, think, and heal. For the first time, scientists have produced detailed maps of these fiber webs across ...

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to ...

In this Innovation Spotlight, Treutlein shares her excitement of using organoids to model the human brain, harnessing AI to accelerate laboratory discoveries, and discusses how massive-scale ...

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the ...

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue. This method, which bypasses traditional stem cell isolation ...

Looking ahead: Every year, tens of thousands of Americans receive organ transplants, yet demand still outstrips supply. Now, a research team at Carnegie Mellon University believes the way out of that ...

This important study advances a new computational approach to measure and visualize gene expression specificity across different tissues and cell types. The framework is potentially helpful for ...

Over one billion people worldwide are over 60, and the population is projected to more than double by 2050. But as more people live into their 60s, 70s, and 80s, health care systems across the globe ...