A recent study published in Cell Metabolism by researchers at the Hebrew University-Hadassah Medical School, Bar-Ilan University and Vanderbilt University has developed a new paradigm for early stages ...

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin ...

Researchers have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a complete structure that ...

Peking University, August 29, 2025: Professor Deng Hongkui’s team from the Peking University School of Life Sciences recently made the first successful differentiation of human pluripotent stem cells ...

Our glycaemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, ...

Hans Clevers, PhD, has been working on organoids from the beginning. He was group leader for twenty years at the Hubrecht Institute and has been head of pharma research and early development (pRED) of ...

Researchers have identified a specific hormone produced by pancreatic beta cells as a direct driver of obesity-linked ...

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells. While islet transplantation has demonstrated promise, its widespread ...

Pancreatic islets from adult mice. On the left, islet composed of different types of endocrine cells. Right: pancreatic islet composed solely of beta cells. Our glycaemic balance is based on the ...