Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

Current drug discovery workflows rely on the synthesis and bioactivity assessment of large compound libraries, both processes which heavily depend on high-throughput (HT) experimentation to be able to ...

The 21st century brought with it an unprecedented number of global and regional economic and political crises, giving rise to a new generation of conflicts in which novel technological, biological, ...

Investigation of leptomeningeal disease in high grade glioma and characterization of molecular alterations. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not ...

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Genome-wide molecular characterization of mucinous colorectal adenocarcinoma. Background: In this study, desorption electrospray ionization (DESI) mass spectrometry (MS) was used in an imaging mode to ...

While each method has its pros and cons, a joint study found that LC-MS provides a clearer, more comprehensive picture of the molecules inside the cells. When testing these methods on cells infected ...

BERKELEY, Calif.--(BUSINESS WIRE)--Newomics, a biotechnology company developing and commercializing mass spectrometry solutions for molecular detection applications, today announced the launch of a ...

Opioids like fentanyl, morphine and oxycodone are the drugs most linked to overdoses in the U.S. Typical screening methods for drug usage involve collection of blood, saliva or urine samples. Now, in ...

A recent study explored rapid evaporative ionization mass spectrometry (REIMS) as a high-throughput, real-time alternative. By analyzing metabolomic fingerprints from pig neck fat, REIMS was combined ...