Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...
Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...
DNA pathways and cancer In terms of basic research, many questions about DNA replication remain, Surtees says. Dividing cells seek to create exact copies of their DNA, which is made up of nucleotide ...
DNA repair mechanism: HELQ helicase remodels stalled replication forks into stable structures, preventing harmful mutations under replication stress. Advanced imaging tool: RF-SIRF maps reversed forks ...
Researchers have resolved the first high-resolution structures of the herpes simplex virus origin-binding protein (OBP), revealing unexpected mechanisms of viral DNA replication and uncovering ...
Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...
Jennifer A. Surtees has long been dedicated to studying genome stability and boosting community involvement in research. With a new National Institutes of Health (NIH) grant, she’ll get to do both.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results