To report our methods for expression and purification of α7 nicotinic acetylcholine receptor (α7-nAChR), a ligand-gated pentameric ion channel and an important drug target. α7-nAChRs of 10 different ...

The new cell-free protein crystallization (CFPC) method developed by Tokyo Tech includes direct protein crystallization and is a major headway in the field of structural biology. This technique will ...

The new cell-free protein crystallization (CFPC) method includes direct protein crystallization and is a major headway in the field of structural biology. This technique will enable the analysis of ...

Engineers devised a way to purify protein drugs during manufacturing. Their approach, which uses nanoparticles to rapidly crystallize proteins, could help make protein drugs more affordable and ...

Antibodies are essential proteins produced by the immune system that recognize and bind to specific targets, known as antigens. Their high specificity and affinity make antibodies invaluable tools in ...

In the downstream portion of any bioprocess, one must pick through the dross before one can seize the gold—the biotherapeutic that the bioprocess was always meant to generate. Unfortunately, the dross ...

The team applied this method to mRNA/saRNA constructs from 1 to 10 kb and assessed pH ranges from 3 to 6. For all the RNA constructs, the J2 immunoblot signal—a marker for dsRNA strands—decreased with ...