While current clinical trials for cardiac regeneration using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) ...

Millions of people around the world die from heart failure every year. In future, a laboratory-grown heart patch could help with severe cases of cardiovascular disease, say scientists behind a ...

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

James Marchant is a postdoctoral researcher in Alexandre Colas’s group at Sanford Burnham Prebys. In this Postdoc Portrait, he shares his work on developing a gene therapy for heart failure, why his ...

University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse ...

A research team at the University of California San Diego has discovered a novel and promising method of treating arrhythmogenic cardiomyopathy (ACM), a rare inherited heart disease that can strike ...

Pioneering research by experts at the University of Sydney, the Baird Institute and the Royal Prince Alfred Hospital in Sydney has shown that heart muscle cells regrow after a heart attack, opening up ...

In developing hearts, cells shuffle around, bumping into each other to find their place, and the stakes are high: pairing with the wrong cell could mean the difference between a beating heart and one ...

Injecting infarcted pig hearts with specially bioengineered cells significantly decreased the infarct area and improved heart function, showing possible clinical relevance “It is widely acknowledged ...

The virus moved through the bloodstream into the heart, where it delivered the cBIN1 gene into heart cells. For this heart failure model, heart failure generally leads to death within a few months.