Metabolic reprogramming is a defining hallmark of breast cancer, encompassing diverse alterations in energy utilisation, biosynthetic pathways and intracellular signalling. Tumour cells frequently ...

Cancer cells rewire their metabolism to support rapid proliferation, survival under stress and metastatic spread. This reprogramming encompasses a shift from mitochondrial oxidative phosphorylation to ...

Cancer is fundamentally a disease of aging. As global populations grow older, the incidence of age-associated cancers, ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

An international research team, led by Justus Liebig University Giessen (JLU), the Institute for Lung Health (ILH) in Giessen ...

Genes tied to cancer progression (angiogenesis, epithelial-mesenchymal transition) were less active. Genes involved in energy production (oxidative phosphorylation) were also less active—a potential ...

GLP-1 drugs commonly used for weight loss and diabetes decreased the risk of cancer spreading in patients with several different types of tumors including breast and lung ...

Engineered silica nanoparticles trigger ferroptosis and immune remodeling in prostate cancer models, sensitizing tumors to immunotherapy.

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...

A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change ...