A genome-wide CRISPR study maps 331 genes essential for early brain development, identifying PEDS1 as a new ...

Which genes are required for turning embryonic stem cells into brain cells, and what happens when this process goes wrong? In a new study published today in Nature Neuroscience, researchers led by ...

By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...

Neurons grown from stem cells in the lab form an interconnected network. In this study, researchers used CRISPR to switch off genes in stem cells and then followed how successfully the cells developed ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...