Purpose: A summary of the basic science underlying the current controversies regarding cyclooxygenase-2 (COX-2)-selective nonsteroidal antiinflammatory drugs (NSAIDs), including data on their ...
Background: We investigated the potential interactions between esomeprazole and a non-selective nonsteroidal anti-inflammatory drug (NSAID; naproxen) or a cyclo-oxygenase (COX)-2-selective NSAID ...
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What's the Difference Between Meloxicam and Ibuprofen?Medically reviewed by Marissa Sansone, MD Ibuprofen and meloxicam are both nonsteroidal anti-inflammatory drugs (NSAIDs) that treat inflammation and pain. Meloxicam is a stronger anti-inflammatory ...
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Celebrex vs. Ibuprofen: Which Is Best for You?It differs from non-selective NSAIDs because it targets the COX-2 enzyme, primarily involved in inflammation. Celebrex works ...
Clinical trials of several COX-2 selective and nonselective NSAIDs of up to 3 years duration have shown an increased risk of serious cardiovascular thrombotic events, including myocardial ...
NSAID research changed radically with the discovery that COX existed in two isoforms: the constitutively expressed COX-1 and an inducible COX-2 isoform 6. Analysis of the distribution of these ...
Clinical trials of several COX-2 selective and nonselective NSAIDs of up to 3 years duration have shown an increased risk of serious cardiovascular thrombotic events, including myocardial ...
In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the rise and fall of VIOXX teach us about physiology?
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