Denver is considered an 8.5-point underdog going into the game in Buffalo. The Bills lead the all-time series against the Broncos 23-17-1, but Denver beat them in Buffalo last season. The Broncos are returning to the NFL playoffs for the first time since winning Super Bowl 50 with Von Miller, who now plays for the Bills.

All-Pro cornerback Patrick Surtain II touted the Denver Broncos' future prospects following Sunday's season-ending loss at Buffalo, expressing his belief that the team is "not that far off" from hosting a playoff game.

Broncos quarterback Bo Nix revealed Monday he played part of his rookie season with transverse process fractures in his back.

The Bills are the No. 2 seed in the AFC playoffs this year and the Broncos are the No. 7 seed. Because the No. 1 seed (the Kansas City Chiefs) get a first-round bye, the No. 2 seed faces the No. 7 seed in the first round.