The bottom line Dermatologists agree that you should generally avoid popping your blisters. Blisters are there for a reason — to protect your skin. So it's best to let them resolve on their own.

Background. A 61-year-old man with type 2 diabetes mellitus presented to a diabetic foot clinic 1 year after he injured his left foot in a slip injury. Examination showed collapse of the ...

and changes to your skin on the bottom of the foot like shearing calluses and blisters,” explains Adenike Sonaike, D.P.M., a podiatrist and medical director with Baker Street Health in Motion.