Somatic cells can reach an aneuploid (and hence potentially tumorigenic) state by losing or gaining single chromosomes 1, or via polyploid intermediates that undergo sequential steps of illegitimate ...

A new interactive map of the proteins involved in cell division gives the ability to track how groups of proteins interact to drive the process of mitosis. Researchers have created a 4D computer ...

The major goal of mitosis is to distribute the genetic material equally between two daughter cells. Movement of the chromosomes on the spindle is driven by both the polymerization dynamics of ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...