The basal ganglia comprise a set of deep brain nuclei—including the striatum, globus pallidus, subthalamic nucleus and substantia nigra—that interact in parallel loops with the cerebral cortex and ...

A) Outline of basal ganglia anatomy in a coronal human brain section. B) UMAP clustering of nuclei from 12 brains based on snRNA-seq data. C) Wiring diagram of basal ganglia circuitry. D) Normalized ...

Most neuroscience studies investigating motor skills are carried out on rodents. In these experiments, rodents are typically tested on simple motor tasks that they can easily complete using motor ...

"We hope that our project will lead to an algorithm for basal ganglia and motor control circuits involved in movement control," says Emory neuroscientist Dieter Jaeger. Emory Photo/Video To move or ...

Researchers have applied a chemogenetic tool in macaque monkeys and suppressed the subthalamic nucleus, a part of the basal ganglia circuitry. The chemogenetic suppression induced unstable movements.

Basal ganglia regions are located in the midbrain. Source: CLIPAREA l Custom media/Shutterstock Stuttering during childhood is a relatively common occurrence. Roughly one in 20 kids (5 percent) go ...

For decades, neuroscientists have thought about communication between the cerebral cortex and the basal ganglia in a fairly linear way. The cortex sends information into the basal ganglia, where that ...

Explore the intricate anatomy, complex neural pathways, and crucial functions of the basal ganglia in regulating both motor control and non-motor behaviors like learning and habit formation. This ...

A UCLA study using mice reveals new insights into the wiring of a major circuit in the brain that is attacked by Parkinson’s and Huntington’s diseases. The findings could hone scientists’ ...