Chromosome 13q linkage promotes RB1 hemizygosity during BRCA2 LOH, lowering the ‘two-hit’ barrier and predisposing to ...

People with a BRCA1 gene mutation, which increases breast and ovarian cancer risk, are also at increased risk of impaired fertility, Monash University-led research has confirmed in preclinical models ...

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Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing ...

A clustered family history of breast, ovarian, and colon cancers appropriately triggered germline testing, with BRCA1 mutation status informing individualized risk stratification and counseling.

For Jackie Tohn, the last few years have been a rollercoaster. The “Nobody Wants This” star has been on a career high. But she’s also been going through a challenging personal health journey behind ...

BRCA testing helps determine if you have a gene mutation that increases your cancer risk. People with a family history of certain cancers may consider BRCA testing. A positive BRCA result does not ...

Gila Pfeffer is a humor writer who splits her time between NYC and London. The following is an adapted excerpt from her memoir, "Nearly Departed: Adventures in Loss, Cancer, and Other Inconveniences." ...

Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more likely ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Eleven years after my mother died in 1994, when I was 31, I learned that a simple blood test could confirm whether I was a carrier of a BRCA gene mutation. Named for the first two letters of "breast" ...