Following spinal cord injury (SCI), the disruption of descending and ascending axonal pathways causes loss of motor, sensory and autonomic function. The ultimate goal of neural repair strategies after ...

Since ancient times it has been recognized that injury to the spinal cord can result in dramatic disability, including both negative symptoms (such as loss of voluntary movement and tactile ...

Researchers have identified a novel molecule in the brain that, after stroke, blocks the formation of new connections between neurons. As a result, it limits the brain’s recovery. In a mouse model, ...

Researchers report that the deletion of the PTEN gene would enhance compensatory sprouting of uninjured CST axons. Furthermore, the deletion up-regulated the activity of another gene, the mammalian ...

Agnes (Yu) Luo, PhD. [University of Cincinnati] After a stroke, extracellular matrix (ECM) molecules known as chondroitin sulfate proteoglycans (CSPGs) become barriers to axonal plasticity and ...

A stroke wreaks havoc in the brain, destroying its cells and the connections between them. Depending on its severity and location, a stroke can impact someone's life forever, affecting motor activity, ...

Researchers at the Hong Kong University of Science and Technology (HKUST) have found a way to stimulate the growth of axons, which may spell the dawn of a new beginning on chronic SCI treatments.