Amiodarone has saved countless lives as one of the most effective antiarrhythmic drugs available to cardiologists, yet its ...

Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their ...

Findings reported in The American Journal of Pathology suggest dofetilide may counteract pathological changes in potassium channels associated with pulmonary arterial hypertension in humans and rats ...

Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line ablation may be more effective in ...

To unravel the mysterious mechanisms of drug potency for the treatment of cardiac arrhythmias, a group of researchers at UC Davis have developed novel simulations that provide insights on vital atomic ...

Antiarrhythmic drugs can cause new, potentially deadly heart arrhythmias. Amiodarone is effective but can cause serious side effects and requires careful monitoring. Multaq cannot be used in people ...

Atrial fibrillation is a chronic, progressive disorder, and persistent forms of atrial fibrillation are associated with increased risks of thromboembolism and heart failure. Catheter ablation as ...

High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a potentially fatal disease caused by obstruction of blood flow in the lungs. A new study in The American Journal ...