The crash of the UPS cargo plane near Louisville Muhammad Ali International Airport happened around 5:15 p.m. Nov. 4.

Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball.

UPS Flight 2976 crashed Tuesday evening as it departed Louisville Muhammad Ali International Airport for Honolulu, according to the FAA.

At least 12 people died when a cargo plane crashed after takeoff in Louisville, Ky. The airport reopened Wednesday morning, but officials warned the death toll could rise.

The UPS freighter that crashed in Louisville was a 34-year old jet. While that’s old for a passenger plane, that’s not so unusual in the world of air cargo.

There was a fire in the UPS plane's left wing and the engine "detached" during takeoff from Louisville International Airport in Kentucky, the NTSB official said.

The left engine came off a doomed United Parcel Service Inc. freighter moments before it crashed in a fireball near the company’s global hub in Kentucky, killing at least 12 people.

A UPS plane with three crew members aboard crashed in Louisville, Kentucky shortly after takeoff Tuesday evening, taking the lives of at least seven people and causing an extensive fire, officials confirmed.