San Francisco 49ers running back Isaac Guerendo (hamstring) was looking like a sure-fire league-winner after a highly ...

RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until ...

The rookie running back did not practice last week and has been officially ruled out of Sunday’s clash at Hard Rock stadium ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

San Francisco 49ers running back Isaac Guerendo appeared on Wednesday's injury report due to a hamstring issue sustained ...

The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

ESPN insider Adam Schefter reported that San Francisco 49ers rookie running back Isaac Guerendo is unlikely to play against ...

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of ...

Isaac Guerendo's status for Thursday's game is "up in the air" after suffering a foot sprain in a win vs. the Bears.

“49ers rookie RB Isaac Guerendo plans to play Thursday night vs. the Rams despite his sprained foot that has left him being ...