Arizona boasts the seventh-ranked defense in the Big 12, holding opponents to minimal yardage by meeting them behind the line of scrimmage. It is Arizona's aggressive defense that has the Wildcats tied for 14th in the FBS in tackles for loss.

Pick OU: Under (53.5) Arizona has covered the spread three times in six games. Arizona is unbeaten ATS (2-0) as a 4.5-point favorite or greater this season. Out of six Arizona games so far this season, three have gone over the total. Colorado's record against the spread in 2025 is 4-4-0.

Optimistic fans at Arizona and Colorado are looking at their remaining schedules and trying to find enough wins to become bowl eligible.

Arizona enters the final stretch of its season sitting at 4-3 overall and 1-3 in Big 12 conference play. The Wildcats need to win at least two of their final fi

Find single game tickets to the Arizona Wildcats vs. Colorado Buffaloes college football Week 10 matchup on Saturday, November 1, 2025 at Folsom Field.