Yreka is the county seat of Siskiyou County, California, United States, near the Shasta River; the city has an area of about 10 square miles, mos…Yreka is the county seat of Siskiyou County, California, United States, near the Shasta River; the city has an area of about 10 square miles, most of it land. As of the 2022 United States Census, the population was 7,827, reflecting an increase from 7,765 counted in the 2010 Census. Yreka is home to the College of the Siskiyous, Klamath National Forest Interpretive Museum and the Siskiyou County Museum.
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