Hampton is a city in Bradford County, Florida, United States. It is located in North Florida. The population was 432 at the 2020 census. Hampton …Hampton is a city in Bradford County, Florida, United States. It is located in North Florida. The population was 432 at the 2020 census. Hampton was first settled in 1859, officially incorporated as the "Town of Hampton" in 1870, and officially reincorporated as the "City of Hampton" in 1925. At the time, it was at the junction of the Georgia Southern and Florida Railway and the Seaboard Air Line Railroad with stations for both.