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WEBThe Single-Cell and Spatial Buyer's Guide Read more. The Sequencing Buyer’s Guide: 6th Edition Read more. Liquid Biopsy Report – A New Era in Disease Detection and Surveillance Read more. Our mission is to deliver the benefits of genomics to patients faster. We achieve this through website content, articles, reports and events.
What is multiplex PCR? - Front Line Genomics
WEBJul 26, 2021 · Multiplex PCR is a technique whereby PCR is used to amplify several different DNA sequences simultaneously. It is a type of target enrichment approach. It was first described in 1988 as a method to detect deletion mutations in the dystrophin gene – the largest known human gene. The dystrophin complex connects the cytoskeleton of …
Sample Preparation for NGS – A Comprehensive Guide
WEBAug 21, 2024 · Step #3: Amplification. This is an optional step, but it is usually required. It is dependent on the application of NGS and the sample size. Amplification becomes essential to obtain enough coverage for reliable sequencing for samples with small amounts of starting material.
About - Front Line Genomics
WEBAddress: Ground Floor, Cromwell House, 15 Andover Road, Winchester, Hampshire, SO23 7BT. Telephone: +44 (0)208 191 8810. Email: [email protected]. At Front Line Genomics our mission is to deliver the benefits of genomics to patients faster. Our social mission drives everything we do.
Long-read sequencing vs short-read sequencing
WEBJul 26, 2021 · Long-read sequencing. Long-read sequencing technologies are capable of reading longer lengths, between 5,000 and 30,000 base pairs. Therefore, they immediately address one of the main challenges faced by short-read sequencing. They sequence a single molecule, eliminating amplification bias, and generate a reasonable length to …
A brief history of Next Generation Sequencing (NGS)
WEBJul 26, 2021 · 2000: Lynx Therapeutics Company launched the first of the NGS technologies, called Massively parallel signature sequencing (MPSS). The company was later bought by Illumina. 2004: 454 Life Sciences marketed a new generation pyrosequencing technology, called the Roche GS20. It was the first NGS platform on the …
DNA Sequencing: How to Choose the Right Technology
WEBAug 6, 2021 · The global market for DNA sequencing is predicted to grow from $15.7 billion in 2021 to $37.7 billion by 2026. The rising prevalence of viral diseases, such as COVID-19, and the increasing cases of cancer globally are likely to drive genomic research and propel the industry at an even more rapid rate.
Myths and facts - Front Line Genomics
WEBOct 20, 2020 · Myths and facts. Fake news and misinformation within medicine and healthcare is a serious problem. The advent and popularisation of social media has enabled the flow of misinformation on a global scale. The COVID-19 pandemic is a key example of how misinformation can be dangerous. Despite evidence highlighting …
Genomics in Drug Discovery & Development
WEBWebinar 1: Leveraging genetics and genomics for drug discovery and development. 13th May – 3pm BST/ 4pm CEST/ 10am EDT. This webinar will focus on the role genetics and genomics is playing in modern drug discovery and how biopharma is approaching genomics-led drug discovery and development across the pipeline, how processes are …
DNA amplification techniques - Front Line Genomics
WEBAug 6, 2021 · DNA nanoball generation: Step #1: The DNA is fragmented and adapter sequences are attached. Step #2: A splint oligonucleotide hybridizes to the ends of the fragments, causing the DNA to form a circle. Step #3: The remaining linear DNA strands are removed, leaving only completed circular single-stranded DNA templates. Step #4: The …